At some point, after a sufficient amount of warnings, then yes, absolutely. We need to bring back tough 3 strike laws. In order for "it" to be "humane" people need to be explicitly told, "Look, if you don't pull it together and stop hurting innocent people and get a job and become a productive member of society then you will be either euthanized or locked up for life." 3 strikes and you're out.
The same goes for war, you can't play "Nice War" with people who are willing to strap dynamite and nails to their chest and blow themselves up in your face. If you aren't willing to use tactical nukes on people like this and kill lots of civilians in the process, then by default you will lose any battle with them. There is nothing more badas* than a kamikaze soldier. American soldiers in the middle east never stood a chance against such a foe. You must make formidable enemies like this fully submit by being more brutal to them than they are to you. The Japanese would have never submitted to the US had it not been for Fat Man and Little Boy.
This is also the only way to stop illegal immigration at our southern boarder. After Trump's border wall (and plenty of written warnings that say "Turn Back Now, You Are About To Die"), there should be a high voltage electric fence peppered with sporadic land mines. It would only take one pregnant mother getting electrocuted to death and/or having her legs blown off for the word to reach Latin America and for all illegal crossings to stop. Although cruel, it would be a small price to pay for instantaneously stopping 10,000 migrants a day from illegally crossing into our once great country.
Some people just won't listen to anything but a barrel of a gun.